[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 12, Issue 1 (3-2013) ::
3 2013, 12(1): 39-0 Back to browse issues page
Dopa-Responsive Dystonia after used Lamotrigine: Case reports
Hossein Ali Ebrahimi, Saeed Ebrahimi
Abstract:   (885 Views)
Epilepsy is a common neurologic disorder affecting approximately 1% of the population. The prevalence of active epilepsy in Kerman,Iran is 7.87/1000 individuals. The past decade has brought many advances to the treatment of epilepsy, including many new pharmacological agents. Lamotrigine is one of the new antiepileptic drugs. Lamotrigine has many side effects; the most important of which are allergic reactions. In this article, the author reports two cases of dopa- responsive dystonia (DRD) after few months administration of lamotrigine for epilepsy. The cases are two girls (4 and 5 years old) who had seizures and received lamotrigine 50 mg/day. They have been free of seizure after treatment but after some time the dystonic attacks developed. Lamotrigine administration discontinued, but dystonic attacks didn’t disappear. Levodopa /carbidopa was started. After a few days, the dystonic pastures disappeared. In conclusion, lamotrigine may introduce dystonia in susceptible patients. These dystonic attacks might beresponsive to levodopa.
Full-Text [PDF 250 kb]   (913 Downloads)    
Article Type: Research Article |
Add your comments about this article
Your username or Email:


XML     Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Ebrahimi H A, Ebrahimi S. Dopa-Responsive Dystonia after used Lamotrigine: Case reports. 3. 2013; 12 (1) :39-0
URL: http://ijpt.iums.ac.ir/article-1-249-en.html

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 12, Issue 1 (3-2013) Back to browse issues page
مجله داروشناسی و درمان شناسی ایران Iranian Journal of Pharmacology and Therapeutics
Persian site map - English site map - Created in 0.07 seconds with 32 queries by YEKTAWEB 4421