[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Registration::
Contact us::
Site Facilities::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
:: Volume 9, Issue 1 (1-2010) ::
3 2010, 9(1): 11-0 Back to browse issues page
Antinociceptive Activity of Mimosa pudica Linn
M. Karthikeyan , M. K. Deepa
Abstract:   (1262 Views)
Normal 0 false false false MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:&quot;Table Normal&quot;; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:&quot;&quot;; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:&quot;Times New Roman&quot;; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} Mimosa pudica Linn (Mimisoideae) is a plant used in traditional medicine for various disorders. The aim of this work was to evaluate the acute toxicity and antinociceptive activity of the aqueous extract of Mimosa pudica in animal models. In the acute toxicity study, a single dose of aqueous extract of 2000 mg kg -1 body weight p.o. was administered. For 48 h, animals showed no clinical signs and mortality. In the acetic acid-induced writhing model, the extract at a dose of 200 & 400 mg kg -1 body weight showed significant ( p <0.001) inhibition of writhing response of 46.24 and 56.0 % respectively. In the hot plate test, the extract produced a significant ( p <0.001) increase in the latency in a dose-related manner. This study established the analgesic properties of Mimosa pudica Linn.
Full-Text [PDF 159 kb]   (1172 Downloads)    
Article Type: Research Article |
Add your comments about this article
Your username or Email:

CAPTCHA


XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Karthikeyan M, Deepa M K. Antinociceptive Activity of Mimosa pudica Linn. 3 2010; 9 (1) :11-0
URL: http://ijpt.iums.ac.ir/article-1-201-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 9, Issue 1 (1-2010) Back to browse issues page
مجله داروشناسی و درمان شناسی ایران Iranian Journal of Pharmacology and Therapeutics
Persian site map - English site map - Created in 0.05 seconds with 39 queries by YEKTAWEB 4642