Anti-Clastogenic Effects of Citral
|
Syed Imam Rabbani , Kshama Devi , Noor Zahra ![](./files/0allsites/images/pubmed20.png) |
|
|
Abstract: (1683 Views) |
Citral is a major constituent of Cymbopogon citratus or lemongrass oil. The anti-clastogenic effect of citral (20 mg/kg) was tested against the known mutagens cyclophoshamide, mitomycin-C and nickel metal (NiCl2) in mice. Micronucleus (MN) frequency was evaluated in both bone marrow and peripheral blood erythrocytes. The sampling was done after 24 h, 48 h and 72 h of clastogen treatment. Results show that citral had significantly (p < 0.01) decreased the frequency of MN induced by the three clastogens in bone marrow and peripheral blood erythrocytes. |
|
|
|
Full-Text [PDF 320 kb]
(834 Downloads)
|
Article Type: Research Article |
|
|
|
|
|
Add your comments about this article |
|
|