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Anti-Clastogenic Effects of Citral
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Syed Imam Rabbani   , Kshama Devi , Noor Zahra |
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Abstract: (1887 Views) |
| Citral is a major constituent of Cymbopogon citratus or lemongrass oil. The anti-clastogenic effect of citral (20 mg/kg) was tested against the known mutagens cyclophoshamide, mitomycin-C and nickel metal (NiCl2) in mice. Micronucleus (MN) frequency was evaluated in both bone marrow and peripheral blood erythrocytes. The sampling was done after 24 h, 48 h and 72 h of clastogen treatment. Results show that citral had significantly (p < 0.01) decreased the frequency of MN induced by the three clastogens in bone marrow and peripheral blood erythrocytes. |
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Full-Text [PDF 320 kb]
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Article Type: Research Article |
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