Blood Glucose Lowering Potential of Stem Bark of Berberis aristata Dc in Alloxan-Induced Diabetic Rats
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J. Kumar Gupta , P. Mishra , Asha Rani , P. Mitra Mazumder |
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Abstract: (1725 Views) |
Normal 0 false false false MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} The present investigation explores the blood glucose lowering potential of Berberis aristata stem bark extract (methanolic extract) in alloxan-induced diabetic rats as well as its in vitro antioxidant property. It is observed that methanolic extract of B. aristata stem bark exhibits significant antidiabetic activity in a dose-dependent manner, but not better than glibenclamide. The extract also has enough reducing power to manifest its antioxidant nature. |
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Article Type: Research Article |
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