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:: Volume 12, Number 1 (3-2013) ::
3 2013, 12(1): 1-0 Back to browse issues page
Salbutamol-Induced Desensitization and Attempts to Resensitize In Vitro
Mohammed Sultan Mohiddin Sajid
Abstract:   (3 Views)
The study was carried out to desensitize spontaneously active isolated chick rectum with salbutamol in log doses starting from 100 nanogram and resensitize with various drugs as a result to revive the desensitized tissue and respond to Salbutamol. The tissue response after desensitization to alpha, beta adrenergic and muscarinic acetylcholine receptor antagonists was isotonically recorded for 10 minutes using thermostatically-controlled organ bath with aeration. The results with prazosin showed that the tissue recovered from desensitization and exhibited spontaneous motility and responded to salbutamol faster.
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Article Type: Research Article |
Received: 2017/11/13
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Sajid M S M. Salbutamol-Induced Desensitization and Attempts to Resensitize In Vitro. 3. 2013; 12 (1) :1-0
URL: http://ijpt.iums.ac.ir/article-1-256-en.html
Volume 12, Number 1 (3-2013) Back to browse issues page
مجله داروشناسی و درمان شناسی ایران Iranian Journal of Pharmacology and Therapeutics
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