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:: Volume 8, Issue 1 (5-2009) ::
3 2009, 8(1): 47-0 Back to browse issues page
Evaluation of Anti-pyretic Potential of Ichnocarpus Frutescens Roots
A. Pandurangan , RL. Khosa , S. Hemalatha
Abstract:   (215 Views)
The methanol extract of Ichnocarpus frutescens R.Br. root (MEIF) was evaluated for its anti-pyretic potential on normal body temperature and yeast-induced pyrexia in albino rats. Yeast suspension (10 ml/kg body wt.) increased rectal temperature 19 h after subcutaneous injection. The MEIF, at doses of 100, 200, and 300 mg/kg body wt., p.o., produced significant reduction in normal body temperature and yeast-provoked elevated temperature in a dose dependent manner. The effect extended up to 5 h after the drug administration. The anti-pyretic effect of MEIF was comparable to that of paracetamol (150 mg/kg body wt., p.o.), a standard anti-pyretic agent.
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Pandurangan A, Khosa R, Hemalatha S. Evaluation of Anti-pyretic Potential of Ichnocarpus Frutescens Roots. 3. 2009; 8 (1) :47-0
URL: http://ijpt.iums.ac.ir/article-1-179-en.html

Volume 8, Issue 1 (5-2009) Back to browse issues page
مجله داروشناسی و درمان شناسی ایران Iranian Journal of Pharmacology and Therapeutics
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