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:: Volume 7, Issue 1 (10-2008) ::
3 2008, 7(1): 115-0 Back to browse issues page
Pathophysiology of Ischemia/Reperfusion-induced Myocardial Injury: What We Have Learned From Preconditioning and Postconditioning?
Pitchai Balakumar , Bharat Pateliya , Gurfateh Singh , Manjeet Singh
Abstract:   (171 Views)
Organ damage after reperfusion of previously viable ischemic tissues is defined as ischemia/reperfusion injury. The pathophysiology of ischemia/reperfusion injury involves cellular effect of ischemia, reactive oxygen species and inflammatory cascade. Protection against ischemia/reperfusion injury may be achieved by preconditioning or postconditioning. In this review, we discuss basic mechanisms involved in the pathophysiology of ischemia/reperfusion injury. Moreover, the pharmacology of preconditioning and postconditioning is delineated.
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Article Type: Research Article |
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Balakumar P, Pateliya B, Singh G, Singh M. Pathophysiology of Ischemia/Reperfusion-induced Myocardial Injury: What We Have Learned From Preconditioning and Postconditioning?. 3. 2008; 7 (1) :115-0
URL: http://ijpt.iums.ac.ir/article-1-146-en.html


Volume 7, Issue 1 (10-2008) Back to browse issues page
مجله داروشناسی و درمان شناسی ایران Iranian Journal of Pharmacology and Therapeutics
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