[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Registration::
Contact us::
Site Facilities::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
:: Volume 6, Issue 2 (11-2007) ::
3 2007, 6(2): 185-0 Back to browse issues page
Calcium Antagonistic Activity of Biophytum Petersianum on Vascular Smooth Muscles of Wistar Rat
Siménou Titrikou , Kwashie Eklu - Gadegbeku , Aklesso Mouzou , Kodjo Aklikokou , Messanvi Gbeassor
Abstract:   (1200 Views)
The whole plant of Biophytum petersianum was extracted with a mixture of water – alcohol (1:1) to evaluate its relaxant effect on aorta rings. In isolated Wistar rat tissue, the hydro-ethanolic extract (0.1; 0.25 and 0.5 mg/ml) non-competitively antagonized calcium chloride and high-K + - induced aorta contractions in a concentration-dependent manner. Moreover, the inhibition of noradrenaline–induced contractions in the presence of extract (1 mg/ml) suggests that the extract has an effect on mobilization of intracellular calcium. These results indicate that hypotensive effect of Biophytum petersianum may result from inhibition of calcium influx via both voltage-and receptor-operated calcium channels.
Full-Text [PDF 117 kb]   (802 Downloads)    
Article Type: Research Article |
Add your comments about this article
Your username or Email:

CAPTCHA


XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Titrikou S, Eklu - Gadegbeku K, Mouzou A, Aklikokou K, Gbeassor M. Calcium Antagonistic Activity of Biophytum Petersianum on Vascular Smooth Muscles of Wistar Rat. 3 2007; 6 (2) :185-0
URL: http://ijpt.iums.ac.ir/article-1-132-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 6, Issue 2 (11-2007) Back to browse issues page
مجله داروشناسی و درمان شناسی ایران Iranian Journal of Pharmacology and Therapeutics
Persian site map - English site map - Created in 0.05 seconds with 39 queries by YEKTAWEB 4642