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Literature & Humanities
http://ijpt.iums.ac.ir
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admin
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14
8888
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en
jalali
1398
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gregorian
2019
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17
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online
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fulltext
en
Biomarker efficacy in multiple sclerosis diagnosis and treatment
Neuropharmacology
مروری
Review Article
The goal in studies concerning biomarkers in autoimmune diseases is finding a marker which fluctuates in correlation with the disease’s severity and settles within normal borders after effective treatment. This marker would later be used as an efficient tool in diagnosis and analysis of medicine clout. It seems the most cogent biomarkers are those measurable in serum or plasma. MS is a neurological disease common within the young adult population with a predictable course, often leading to life-immersing disability. The prognosis, however difficult and limited, is currently possible via diagnostic tests (brain MRI) or clinical information (severity and degrees of disability). Many studies have been conducted in an effort to detect an adequate biomarker. It is still often overlooked that a reliable biomarker should both be clinically applicable and functional is prognosis; as this is what could lead to timely treatment.
MS biomarkers, Autoimmune disease, Demyelination, MicroRNAs
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http://ijpt.iums.ac.ir/browse.php?a_code=A-10-170-1&slc_lang=en&sid=1
FATEMEH
GHASEMI SAKHA
sakha62@mail.com
10031947532846002033
10031947532846002033
No
Department of Biology, Damghan Branch, Islamic Azad University, Damghan, Iran
SEYED MOHAMMAD
MOAZZENI
moazzeni@modares.ac.ir
10031947532846002034
10031947532846002034
No
Department of immunology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
FARNAZ
ETESAM
fa.etesam@gmail.com
10031947532846002035
10031947532846002035
No
Psychosomatic Medicine Research Center, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran
AMIRREZA
AZIMI SAEEN
amirreza_azimi@yahoo.com
10031947532846002036
10031947532846002036
Yes
MS Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran
GHOLAMHASSAN
VAEZI
gh.vaezi@yahoo.com
10031947532846002037
10031947532846002037
No
Department of Biology, Damghan Branch, Islamic Azad University, Damghan, Iran