2
1
3
Literature & Humanities
http://ijpt.iums.ac.ir
1
admin
9
10
8
7
14
8888
13
en
jalali
1397
3
1
gregorian
2018
6
1
16
1
online
1
fulltext
en
Validation of Integral System Yeast Plus for rapid identification and determination of antifungal susceptibility profile of clinically important Candida species
Other
پژوهشي
Research Article
<div style="text-align: justify;">Precise identification of microorganisms involved in candidiasis together with antifungal susceptibility evaluation could help clinicians to prescribe appropriate medicine, especially in patients with critical conditions. The present study has been conducted to evaluate discriminatory power of Integral System Yeast Plus (ISYP) for rapid identification and determination of antifungal susceptibility of clinically important <em>Candida</em> species (sp.). Validation of ISYP results was performed using molecular and Broth Micro Dilution (BMD) assays. Referring to the present results, it can be said that ISYP was to some extent successful for identification of<em> C. albicans</em> isolates. Major misidentification was observed in cases of non <em>C. albicans</em> sp. (NAC) in comparison with sequencing results<strong><em>.</em></strong> The relatively unsatisfied outcome of ISYP performance was correlated to antifungals susceptibility assay as well. It is noteworthy to emphasize the potential advantages of ISYP for simultaneous identification of <em>Candida</em> sp. together with antifungal susceptibility evaluation that brings hope to the defeat of severe complications. But an essential defect was observed in both identification and antifungal susceptibility tests.</div>
Candida albicans, Non-albicans Candida, Integral System Yeast Plus
1
4
http://ijpt.iums.ac.ir/browse.php?a_code=A-10-61-1&slc_lang=en&sid=1
MITRA
BARATI
mitrabaraty@yahoo.com
10031947532846001583
10031947532846001583
No
MONA
GHAZANFARI
fattahiazam.mycologist@gmail.com
10031947532846001584
10031947532846001584
No
FATEMEH
BAZRAFSHAN
rahaazadi@gmail.com
10031947532846001585
10031947532846001585
No
KOOSHA
FARHADI
mehraban.fth@gmail.com
10031947532846001586
10031947532846001586
No
MEHRY
NAGHDALIPOOR
emelimoradi@gmail.com
10031947532846001587
10031947532846001587
No
ZEYNAB
FAKHRI
10031947532846001588
10031947532846001588
Yes
Department of Infectious Disease, Rasul-e Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
AZAM
FATTAHI
10031947532846001589
10031947532846001589
No
fattahiazam63@gmail.com