2
1
3
Literature & Humanities
http://ijpt.iums.ac.ir
1
admin
9
10
8
7
14
8888
13
en
jalali
1388
2
1
gregorian
2009
5
1
8
1
online
1
fulltext
en
Hypoglycemic Activity of Ethanolic Extract of Cinnamomum tamala Leaves in Normal and Streptozotocin Diabetic Rats
پژوهشي
Research Article
Indian traditional system of medicine has been used plants and herbs for treatment of diabetes since time of Vedic glory. In this regard many plants still untouched, having remarkable efficacy. The blood sugar lowering effect of 95% ethanolic extract of C. tamala ( Hamm.) Nees. & Eberm., leaves was investigated at single oral dose of 250mg/kg body weight in normal fasted, fed, glucose loaded and streptozotocin-induced diabetic male albino rats. Further, effect of crude extract was studied on muscle glycogen content and histology of pancreatic β-cells granularity of normal rats. Significant blood glucose lowering was observed in fasted, fed and diabetic rats. Extract also suppressed the peak value significantly in the glucose fed rats. Marked degranulation in β-cells of treated rats suggests insulin secretogogue effect of extract that probably be increased the muscle glycogen store and produced hypoglycemic response.
17
0
http://ijpt.iums.ac.ir/browse.php?a_code=A-10-100-193&slc_lang=en&sid=1
Rahul
Gupta
1003194753284600647
1003194753284600647
No
Pramod Kumar
Agnihotri
1003194753284600648
1003194753284600648
No
Samta
Johri
1003194753284600649
1003194753284600649
No
Anand Murari
Saxena
1003194753284600650
1003194753284600650
No