en پژوهشي Research Article The antioxidant activity of the melia azedarach was investigated in rats with ethanol-induced erythrocyte damage. Chronic administration of ethanol (20% w/v, 2 g/kg.p.o.,daily for four weeks) increased the level of lipid peroxidation (LPO), decreased the activity of superoxide dismutase (SOD) and catalase and reduced the content of glutathione (GSH). The concurrent treatment of ethanol-administered rats with melia azedarach (500mg/kg, p.o.) prevented the above ethanol-induced changes and the effect was compared with combination of vitamin E and C. It can therefore be suggested that the leaves of melia azedarach posses an erythrocyte protective activity against drug-induced oxidative stress. 31 0 http://ijpt.iums.ac.ir/browse.php?a_code=A-10-100-171&slc_lang=en&sid=1 Mohd Fazil Ahmed 1003194753284600561 1003194753284600561 No Mohd Ibrahim 1003194753284600562 1003194753284600562 No Mohd Ashwaq Ahmed 1003194753284600563 1003194753284600563 No Hameed Thayyil 1003194753284600564 1003194753284600564 No Khaja Zameeruddin 1003194753284600565 1003194753284600565 No