en پژوهشي Research Article Rheumatoid arthritis is a chronic multi-system disease of unknown cause. It affects the people in their prime of life, predominantly between the ages of 20-50 years with unpredictable course. Sudard is used in the ayurvedic system of medicine for the treatment of inflammation and pain associated with rheumatoid arthritis, osteo-arthritis, frozen shoulder, sciatica, ankylosing spondylitis and chronic backache. Our study was aimed to evaluate efficacy of sudard using different animal models such as formalin (2% v/v) induced acute inflammation, carrageen (1% v/v) induced polyarthritis, adjuvant induced arthritis, subacute inflammation by sponge implantation technique and analgesic activity by Eddy’s hot plate method. The results indicate that the formulation sudard possesses anti-inflammatory, anti-arthritic and analgesic activities in the experimental animal models. 71 0 http://ijpt.iums.ac.ir/browse.php?a_code=A-10-100-118&slc_lang=en&sid=1 Mohammed Asad 1003194753284600369 1003194753284600369 No Koteshwar Prasad 1003194753284600370 1003194753284600370 No Licto Thomas 1003194753284600371 1003194753284600371 No Jagadish V Kamath 1003194753284600372 1003194753284600372 No