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Showing 2 results for Kavimani

R Dhanapal, S Kavimani, V Swamy, Malaya Gupta, Sk Basu,
Volume 4, Issue 1 (6-2005)
Abstract

Ethanol (90%) extract of Ammania baccifera (L.) whole plant (EEAB) was evaluated for possible antister-oidogenic activity in mature female mice ovaries. The ethanol extract at the doses of 100, 200 and 400 mg/kg body weight (i.p) arrested the normal estrus cycle at dioestrus phase and significantly decreased weight of ovaries. The cholesterol and ascorbic acid content in ovaries were significantly elevated in treated mice. The extract also significantly inhibited the activity of ?5-3-hydroxy steroid dehydrogenase (?5-3-HSD) and Glucose-6-phosphate dehydrogenase (G-6-PD), the two key enzymes involved in ovarian steroidogenesis. Results of this study suggested that the ethanol extract of whole plant of Ammania baccifera (L.) acts as an antisteroidogenic agent.
Varadarasou Mouttaya Mounnissamy, Subramanian Kavimani, Vaithilingam Balu, Sabarimuthu Darlin Quine,
Volume 6, Issue 2 (11-2007)
Abstract

Cansjera rheedii is widely used as a traditional medicine for the treatment and control of a variety of human inflammatory ailments by the fishermen of Auroville.   In the present study, the anti-inflammatory and membrane stabilizing property of Ethanol Extract of Cansjera rheedii J. Gmelin (EECR) was evaluated in rat using the Human Red Blood Cells (HRBC) membrane stabilization method and carrageenin-induced acute paw edema model.   The extract in concentration of 6-100µg/ml showed a dose-dependent inhibition of haemolysis of erythrocytes induced by hypotonic solution.   Oral pre-treatment with EECR (250mg/kg) inhibited carrageenin-induced paw edema (41.93%) within 3 hrs.   It is concluded that the extract possess anti-inflammatory as well as membrane stabilizing property.

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مجله داروشناسی و درمان شناسی ایران Iranian Journal of Pharmacology and Therapeutics
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