|
|
|
 |
Search published articles |
 |
|
Showing 2 results for Islam
Mohammad Ashraful Alam, Md. Abu Bin Nyeem, Md. Abdul Awal, Mahbub Mostofa, Nusrat Islam, Sheikh Jamal Uddin,
Volume 5, Issue 2 (12-2006)
Abstract
The ethanol extract of the flowering top of Rosa damascena (Rosaceae) was assessed for neuropharmacological activities in mice using a number of experimental models. It significantly prolonged the pentobarbitone-induced sleeping time in mice, and showed mild to moderate central nervous system depressant activity when assessed by the hole cross and the open field tests in mice model when given at the doses of 250 and 500 mg/kg body weight. At the same dose levels, the extract dose-dependently inhibited acetic acid-induced writhing in mice. On the basis of these findings, it can be assumed that the extract exerts its depressant effect on the central nervous system in mice.
M. Kaisarul Islam, I. Zahan Eti, J. Ahmed Chowdhury,
Volume 9, Issue 1 (1-2010)
Abstract
Normal 0 false false false MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} The stem bark of Oroxylum indicum ( Fam. Bignoniaceae) was extracted with methanol. The methanol extract was fractionated with pet ether, chloroform, hexane and carbon tetrachloride using modified Kupchan partitioning method. Extensive chromatographic separation and purification with the organic solvent was done. One compound was extracted from the n-hexane fraction of stem bark of O. indicum which was then confirmed as flavonoid type of compound by using 1 H NMR spectrometric analysis. Three fractions (hexane, carbon tetrachloride, chloroform), obtained from methanolic crude extract, were tested for antimicrobial activity by standard disc diffusion method. The extracts were found to show antimicrobial activities towards the gram-positive and gram-negative bacteria, and some fungi . The results were compared with same microbial strains against a standard antibiotic disc of ampicillin (10 m g/disc).
|
|
