Vrushabendra Swamy, Sridhar Chandanam, Sreenivasa Rao, R Dhanapal, V Balamuralidhar, Ashoka Babu,
Volume 4, Issue 1 (6-2005)
Abstract
The methanolic extract of fruit of Benincasa hispida (BHFE) was evaluated for its antidiarrheal potential against several experimental models of diarrhea in rats. BHFE treated animals showed significant inhibi-tory activity against castor oil induced diarrhea and inhibited PGE2 induced enter pooling in rats. It also showed significant reduction in gastro intestinal motility following charcoal meal in rats. The result ob-tained and establishes the efficacy of BHFE as an antidiarrheal agent.
