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Studies of Cytotoxic Potential of Aqueous Fruit Extract of Cucumis melo.Linn in Prostate Cancer Cell lines PC-3 Using MTT and Neutral Red Assay
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Sibi Perumbamkudiyil Ittiyavirah   , Ann George , Anju M. Santhosh , Sudhi T. Kurian , Prinsy Pappachan , Gifty Jacob |
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Abstract: (1730 Views) |
| The objective of the study was to evaluate the cytotoxic effects of aqueous extract of Cucumis melo fruit on human prostate cancer cell line (PC-3) using MTT and neutral red assays. The crude aqueous extract of C. melo was prepared by cold maceration method, filtered, concentrated and tested on PC-3 cell line. Dose-dependent cytotoxic activities were exhibited on human prostate carcinoma PC-3 cell line. As the dose of the extract increased, the number of viable cells decreased. This confirms the cytotoxic potential of the fruit of C. melo. |
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Full-Text [PDF 270 kb]
(812 Downloads)
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Article Type: Research Article |
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