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Studies of Cytotoxic Potential of Cucumis melo. Linn Fruit Aqueous Extract in Prostate Cancer Cell lines PC-3 Using MTT and Neutral Red Assay
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Sibi Perumbamkudiyil Ittiyavirah   , Ann George , Anju M Santhosh , Sudhi T Kurian , Prinsy Pappachan , Gifty Jacob |
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Abstract: (1681 Views) |
| The objective of the study was to evaluate thecytotoxic effects of aqueous fruit extract of Cucumis melo in human prostate cancer cell line (PC-3) using MTTand neutral red assays. The crude aqueous extract of C.melo was prepared by cold maceration method, filtered,concentrated and tested on PC-3 cell line. Dose-dependent cytotoxic activitieswere exhibited by human prostate carcinoma PC-3 cell line. As the dose of theextract increased, the number of viable cells decreased. This confirms the anti-cancerand cytotoxic potential of the fruit of C.melo. |
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Article Type: Research Article |
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