:: Volume 12, Issue 1 (3-2013) ::
3 2013, 12(1): 24-0 Back to browse issues page
Studies of Cytotoxic Potential of Cucumis melo. Linn Fruit Aqueous Extract in Prostate Cancer Cell lines PC-3 Using MTT and Neutral Red Assay
Sibi Perumbamkudiyil Ittiyavirah, Ann George, Anju M Santhosh, Sudhi T Kurian, Prinsy Pappachan, Gifty Jacob
Abstract:   (956 Views)
The objective of the study was to evaluate thecytotoxic effects of aqueous fruit extract of Cucumis melo in human prostate cancer cell line (PC-3) using MTTand neutral red assays. The crude aqueous extract of C.melo was prepared by cold maceration method, filtered,concentrated and tested on PC-3 cell line. Dose-dependent cytotoxic activitieswere exhibited by human prostate carcinoma PC-3 cell line. As the dose of theextract increased, the number of viable cells decreased. This confirms the anti-cancerand cytotoxic potential of the fruit of C.melo.
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Volume 12, Issue 1 (3-2013) Back to browse issues page