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1
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Literature & Humanities
http://ijpt.iums.ac.ir
1
admin
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10
8
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14
8888
13
en
jalali
1385
9
1
gregorian
2006
12
1
5
2
online
1
fulltext
en
Bioactive Alkaloid from Sida cordifolia Linn. with Analgesic and Anti-Inflammatory Activities
پژوهشي
Research Article
In the present study, the analgesic and anti-inflammatory activities of a new alkaloid (5′-Hydroxymethyl-1′-(1,2,3,9-tetrahydro-pyrrolo [2,1-b] quinazolin-1-yl)-heptan-1-one) (compound 1), isolated from Sida cordifolia Linn. was investigated in animal models. The analgesic activity was investigated in the acetic acid induced writhing and the radiant heat tail flick model in mice and the carrageenan induced rat paw edema model was used for anti-inflammatory study. The compound produced significant ( p <0.01) analgesic activity in both models. The compound also exhibited significant ( p <0.01) inhibition of rat paw edema induced by carrageenan. These results indicated that compound 1 possessed analgesic and anti-inflammatory activities .
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http://ijpt.iums.ac.ir/browse.php?a_code=A-10-100-96&slc_lang=en&sid=1
Ranajit Kumar
Sutradhar
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1003194753284600302
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AKM Matior
Rahman
1003194753284600303
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No
Mesbahuddin
Ahmad
1003194753284600304
1003194753284600304
No
Sitesh Chandra
Bachar
1003194753284600305
1003194753284600305
No
Achinto
Saha
1003194753284600306
1003194753284600306
No
Samar
Kumar Guha
1003194753284600307
1003194753284600307
No