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Literature & Humanities
http://ijpt.iums.ac.ir
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admin
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10
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8888
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en
jalali
1385
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gregorian
2006
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online
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fulltext
en
Anti-Hyperglycemic and Renal Protective Activities of Andrographis paniculata Roots Chloroform Extract
پژوهشي
Research Article
The chloroform extract of Andrographis paniculata roots was tested for its antihyperglycemic activity in alloxan induced diabetic rats using chronic and acute studies. The blood glucose lowering activity was determined after oral administration at doses of 50, 100 and 150 mg/kg body weight in acute study. Where as in case of chronic study blood glucose, protein, albumin and creatinine levels were estimated after 4 weeks of treatment at the dose of 300 mg/kg. Significant reductions in blood glucose levels were observed in both acute and chronic studies. The extract significanly inhibited the induction of albuminuria, proteinemia and uremia. The present study clearly indicated a significant antidiabetic activity with the chloroform extract of A. paniculata roots and supports the traditional usage of the plant by Ayurvedic physicians for the control of diabetes. Also the extract is useful in preventing the incidence of long-term complication, diabetic nephropathy.
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http://ijpt.iums.ac.ir/browse.php?a_code=A-10-100-87&slc_lang=en&sid=1
Nalamolu
Koteswara Rao
1003194753284600267
1003194753284600267
No