RT - Journal Article T1 - Sildenafil Determination in Various Matrices: A Review JF - iums-ijpt YR - 2005 JO - iums-ijpt VO - 4 IS - 2 UR - http://ijpt.iums.ac.ir/article-1-69-en.html SP - 72 EP - 0 AB - Determination of sildenafil by various methods and in various media is reviewed in this paper. The methods used consist of ultraviolet (UV) spectroscopy, thin layer chromatography (TLC), and high-performance liquid chromatography (HPLC). These methods were used to determine the amount of sildenafil in pharmaceutical preparations, soft drinks, and biological liquids. HPLC was used for evaluation of pharmacokinetic parameters of sildenafil. It is concluded that HPLC is the most reliable and applicable method in this regard. LA eng UL http://ijpt.iums.ac.ir/article-1-69-en.html M3 ER -