AU - Swamy, Vrushabendra AU - Chandanam, Sridhar AU - Rao, Sreenivasa AU - Dhanapal, R AU - Balamuralidhar, V AU - Babu, Ashoka TI - Antidiarrheal Evaluation of Benincasa hispida (Thunb.) Cogn. Fruit Extracts PT - JOURNAL ARTICLE TA - iums-ijpt JN - iums-ijpt VO - 4 VI - 1 IP - 1 4099 - http://ijpt.iums.ac.ir/article-1-46-en.html 4100 - http://ijpt.iums.ac.ir/article-1-46-en.pdf SO - iums-ijpt 1 ABĀ  - The methanolic extract of fruit of Benincasa hispida (BHFE) was evaluated for its antidiarrheal potential against several experimental models of diarrhea in rats. BHFE treated animals showed significant inhibi-tory activity against castor oil induced diarrhea and inhibited PGE2 induced enter pooling in rats. It also showed significant reduction in gastro intestinal motility following charcoal meal in rats. The result ob-tained and establishes the efficacy of BHFE as an antidiarrheal agent. CP - IRAN IN - LG - eng PB - iums-ijpt PG - 24 PT - Research Article YR - 2005