TY - JOUR T1 - Antibacterial activity and cytotoxicity screening of Sumatran Kaduk (Piper sarmentosum Roxb) TT - JF - iums-ijpt JO - iums-ijpt VL - 10 IS - 1 UR - http://ijpt.iums.ac.ir/article-1-223-en.html Y1 - 2011 SP - 1 EP - 0 N2 - Phytochemical investigations of Piper sarmentosum Roxb., yielded four compounds; three amides, identified as 3-(3’,4’,5’-trimethoxyphenylpropanoyl) pyrrolidine, 3-(4’-methoxyphenylpropanoyl) pyrrole, N -(3-phenylpropanoyl) pyrrole and a sterol namely β -sitosterol . 3-(4’-Methoxyphenylpropanoyl) pyrrole was found for the first time in this Piper species. All chemical constituents were tested for their antibacterial activity using disk diffusion method and cytotoxicity screening using sul-forhodamine B (SRB) assay. All of the compounds were found only active towards gram-positive bacteria except 3-(4’-methoxyphenylpropanoyl) pyrrole with no activity against both gram-positive and gram-negative bacteria. Meanwhile, the cytotoxicity screening using SRB assay indicated that none of these compounds was active as an anticancer agent. M3 ER -