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:: Volume 12, Issue 1 (3-2013) ::
3 2013, 12(1): 24-0 Back to browse issues page
Studies of Cytotoxic Potential of Cucumis melo. Linn Fruit Aqueous Extract in Prostate Cancer Cell lines PC-3 Using MTT and Neutral Red Assay
Sibi Perumbamkudiyil Ittiyavirah , Ann George , Anju M Santhosh , Sudhi T Kurian , Prinsy Pappachan , Gifty Jacob
Abstract:   (155 Views)
The objective of the study was to evaluate thecytotoxic effects of aqueous fruit extract of Cucumis melo in human prostate cancer cell line (PC-3) using MTTand neutral red assays. The crude aqueous extract of C.melo was prepared by cold maceration method, filtered,concentrated and tested on PC-3 cell line. Dose-dependent cytotoxic activitieswere exhibited by human prostate carcinoma PC-3 cell line. As the dose of theextract increased, the number of viable cells decreased. This confirms the anti-cancerand cytotoxic potential of the fruit of C.melo.
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Ittiyavirah S P, George A, Santhosh A M, Kurian S T, Pappachan P, Jacob G. Studies of Cytotoxic Potential of Cucumis melo. Linn Fruit Aqueous Extract in Prostate Cancer Cell lines PC-3 Using MTT and Neutral Red Assay. 3. 2013; 12 (1) :24-0
URL: http://ijpt.iums.ac.ir/article-1-251-en.html


Volume 12, Issue 1 (3-2013) Back to browse issues page
مجله داروشناسی و درمان شناسی ایران Iranian Journal of Pharmacology and Therapeutics
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