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:: Volume 6, Issue 2 (11-2007) ::
3 2007, 6(2): 191-0 Back to browse issues page
In Vitro Antioxidant and Free Radical Scavenging Activity of Alstonia scholaris Linn. R.Br.,
Arulmozhi Sinnathambi , Papiya Mitra Mazumder , Purnima Ashok , L. Sathiya Narayanan
Abstract:   (231 Views)
The present work is carried out to study the antioxidant potential of ethanolic extract of Alstonia scholaris Linn. ( Apocynaceae ) using various in vitro tests including 1,1-diphenyl-2-picryl-hydrazil (DPPH . ) free radical scavenging, metal ion chelating, hydrogen peroxide scavenging, superoxide anion radical scavenging, and ferric thiocyanate reducing ability. &nbsp; Ethanolic extract of Alstonia scholaris had significant ( p <0.01) (DPPH . ) free radical scavenging (63%), metal ion chelating (74.88%), hydrogen peroxide scavenging (72.28%), superoxide anion radical scavenging (67.66%) and significant ( p <0.05) ferric thiocyanate reducing activities. &nbsp; These various antioxidant activities were compared to standard antioxidants such as butylated hydroxyanisole &nbsp; (BHA), butylated hydroxy toluene (BHT), l- ascorbic acid and a -tocopherol. &nbsp; These results indicate that ethanolic extract of Alstonia scholaris Linn. possess antioxidant property. The results observed were comparable to antioxidant properties of BHA, BHT, l- ascorbic acid and a -tocopherol.
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Sinnathambi A, Mazumder P M, Ashok P, Narayanan L S. In Vitro Antioxidant and Free Radical Scavenging Activity of Alstonia scholaris Linn. R.Br.,. 3. 2007; 6 (2) :191-0
URL: http://ijpt.iums.ac.ir/article-1-131-en.html


Volume 6, Issue 2 (11-2007) Back to browse issues page
مجله داروشناسی و درمان شناسی ایران Iranian Journal of Pharmacology and Therapeutics
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