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:: Volume 13, Issue 1 (8-2015) ::
3 2015, 13(1): 19-0 Back to browse issues page
Studies of Cytotoxic Potential of Aqueous Fruit Extract of Cucumis melo.Linn in Prostate Cancer Cell lines PC-3 Using MTT and Neutral Red Assay
Sibi Perumbamkudiyil Ittiyavirah , Ann George , Anju M. Santhosh , Sudhi T. Kurian , Prinsy Pappachan , Gifty Jacob
Abstract:   (38 Views)
The objective of the study was to evaluate the cytotoxic effects of aqueous extract of Cucumis melo fruit on human prostate cancer cell line (PC-3) using MTT and neutral red assays. The crude aqueous extract of C. melo was prepared by cold maceration method, filtered, concentrated and tested on PC-3 cell line. Dose-dependent cytotoxic activities were exhibited on human prostate carcinoma PC-3 cell line. As the dose of the extract increased, the number of viable cells decreased. This confirms the cytotoxic potential of the fruit of C. melo.
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Ittiyavirah S P, George A, M. Santhosh A, T. Kurian S, Pappachan P, Jacob G. Studies of Cytotoxic Potential of Aqueous Fruit Extract of Cucumis melo.Linn in Prostate Cancer Cell lines PC-3 Using MTT and Neutral Red Assay. 3. 2015; 13 (1) :19-0
URL: http://ijpt.iums.ac.ir/article-1-270-en.html
Volume 13, Issue 1 (8-2015) Back to browse issues page
مجله داروشناسی و درمان شناسی ایران Iranian Journal of Pharmacology and Therapeutics
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