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:: Volume 11, Number 2 (12-2012) ::
3 2012, 11(2): 64-0 Back to browse issues page
Effects of Coenzyme Q10 on Hemoglobin A1C, Serum Urea and Creatinine in Alloxan-Induced Type 1 Diabetic Rats
Hassan Ahmadvand
Abstract:   (32 Views)
Coenzyme Q 10 is a natural antioxidant and free radicals scavenger. In the present study, we examined effect of coenzyme Q 10 on hemoglobin A 1C , serum urea and creatinine in alloxan-induced Type 1 diabetic rats. Thirty Sprage-Dawley male rats were divided into three groups randomly; group one as control, group two diabetic untreatment, and group three treatments with coenzyme Q 10 (15 mg/kg i.p daily), respectively . Diabetes was induced in the second and third groups by alloxan injection subcutaneously. After 8 weeks, animals were anaesthetized; blood samples were collected to measure the hemoglobin A 1C , serum glucose, urea and creatinine . Coenzyme Q 10 significantly decreased hemoglobin A 1C , serum glucose, urea and creatinine . Coenzyme Q 10 exerts beneficial effects on the hemoglobin A 1C and serum glucose in alloxan-induced type 1 diabetic rats.
     
Type of Study: Research | Subject: General
Received: 2017/05/13
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Hassan Ahmadvand. Effects of Coenzyme Q10 on Hemoglobin A1C, Serum Urea and Creatinine in Alloxan-Induced Type 1 Diabetic Rats. 3. 2012; 11 (2) :64-0
URL: http://ijpt.iums.ac.ir/article-1-246-en.html
Volume 11, Number 2 (12-2012) Back to browse issues page
مجله داروشناسی و درمان شناسی ایران Iranian Journal of Pharmacology and Therapeutics
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